Endocrine Abstracts

BackgroundThyroid diseases and diabetes are the two most common endocrinopathies. A relationship between these two conditions is suggested by many studies, as diabetic population seems to present increased thyroid impairment. However, clinical data are still very sparse.AimTo evaluate thyroid morphologic characteristics among patients with different glucose tolerance status.Material and...

Adrenocortical cancer (ACC) is a rare and aggressive malignancy. Currently the main therapeutic option is surgery, but due to difficult and delayed diagnosis and to the onset of metastases, medical therapy is often tried. ACC treatment is mainly represented by Mitotane alone or in association with chemotherapy, with variable results. Understanding the molecular mechanisms that regulate ACC proliferation could be useful to identify new therapeutic options. Sunitinib, a multitar...